Drug Profile: HCG Human Chorionic Gonadotropin

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Drug Profiles--> HCG

HCG (HUMAN CHORIONIC GONADOTROPIN)

Substance: chorionic gonadotropin
Trade Names:
A.PL.	5000 LU., 10000 I.U., 20000 LU. amp.;	Wyeth-Ayerst U.S,
Biogonadyl	500 1-U., 2000 I.U. amp.;	Biomed PL
C.G. (o.c.)	10000 I.U. amp.;	Sig U.S.
Choragon	1500 I.U., 5000 I.U. amp.;	Ferring G
Chorex	5000 I.U., 10000 1.U. amp.;	Hyrex U.S.
Chorigon (o.c.)	10000 I.U. amp.;	Dunhall U.S.
Chorion-Plus (o.co.)	10000 I.U. amp.;	Pharmex U.S.
Choron 10	1000 LU-, 10,000 1-U. amp.	Forest U.S.
Corgonject (o.c.)	5000 I.U. amp.;	Mayrand U.S.
Follutein (o.c.)	10000 I.U. amp.;	Squibb Mark
Gestyl	1000 I.U. amp.;	Organon BG
Glukor (o.c.)	10000 I.U. amp.;	Hyrex U.S.
Gonadotraphon	500 I.U.' 1000 I.U. 5000 LU. amp.;	Paines+Byrne GB
Gonadotrafon LH	125 I.U., 250 1.U., 1000 I.U. amp.;	Amsa I
Gonadotrafon LH	2000 I.U., 5000 I.U., amp.;	Amsa I
G. chor. "Endo"	500 I.U., 1500 I.U., 5000 LU. amp.;	Organon FR
Gonadotropyl	5000 I.U. amp.;	Roussel Mexico
Gonic (o.c.)	1000 I.U. amp.;	Hauck U.S.
Gonic	1000 I.U. amp.;	Roberts U.S.
Harvatropin	10000 I.U. amp.;	Harvey U.S.
H.C.G. (o.c.)	1000 I.U., 10000 I.U. amp.;	Huffman U.S.
H.C.G.	5000 I.U., 10000 I.U. amp.;	Pharmed Group U.S.
HCG	5000 1-U., 10000 I.U. amp.;	Steris U.S.
HCG Lepori	500 I.U., 1000 I.U., 2500 I.U. amp.;	Lepori ES
Neogonadil Bruco	1000 W. amp.;	Opocrin I(o.c.)
Physex	1500 I.U., 3000 I.U., amp.;	Leo DK, NO
Physex Leo	500 I.U., 1500 1-U., 5000 I.U. amp.;	Leo ES
Praedyn	1500 I.U., 3000 I.U. amp.;	Leciva CZ
Predalon	500 I.U., 5000 I.U. amp.;	Organon G
Pregnesin	250 I.U., 500 1.U., 1000 I.U. amp.;	Serono G, CZ
Pregnesin	2500 I.U., 5000 I.U. amp.;	Serono G, CZ
Pregnyl	10000 I.U. amp.;	Organon U.S.
Pregnyl	100 I.U. amp.;	Organon 1, BG
Pregnyl	500 I.U., 1500 1.U., 5000 I.U. amp.;	Organon A, B, CH, GB, BG, GR, 1, NL, PL, S, FI; YU; CZ, NO, HU, Medika/ Santa A
Pregnyl	1500 I.U., 5000 I.U. amp.;	Organon Mexico
Primogonyl (o.c.)	250 I.U., 500 LU. amp.;	Schering A
Primogonyl	250 I.U., 500 I.U. amp.;	Schering CH, G,CZ
Primogonyl	1000 I.U., 5000 I.U. amp.;	Schering G, CH, YU, CZ
Profasi	10000 I.U. amp.;	Serono CH, B, Mexico, S, Fl, GB,NO, NL
Profasi	500 I.U. amp.;	Serono CH, GB, Mexico, HU, FR
Profasi	1000 I.U. amp.;	Serono HU, NL
Profasi	1500 I.U. amp.;	Serono FR
Profasi	2000 I.U., 5000 I.U. amp.;	Serono A, B, CH, DK, HU, GB, GR, S,FR, NL, NO, Mexico
Profasi HP	5000 I.U., 10000 I.U. amp.;	Serono U.S.
Profasi HP	250 LU., 2000 1-U., 5000 LU. amp;	Serono 1
Profasi HP	500 1.U., 1000 I.U., amp;	Serono I
Profasi HP	500 1-U., 1000 1-U., 2500 1.11- amp;	Serono ES
Rochoric (o.c.)	10000 LU. amp.;	Rocky-Mount. U.S.
Veterinary: Brumegon	1000 LU. amp.;	Hydro G
Choriolutin	1500 1.U., 5000 LU;	Albrecht G
Chor.Gonadotropin	10000 I.U.	Steris U.S.
Chorulon vet.	injection solution	Intervet DK
Chorvlon (o.c.)	1500 I.U. amp.;	Werfft-Chemie A
Ekluton	1500 LU., 5000 1.U.;	Vemie G
Gonadoplex vet.	injection solution;	Leo DK
HCG	10000 I.U.	Steris U.S.
Ovogest	1500 In, 5000 1-U.;	Hydro G
Ovo-Gonadon	500 LU.;	Alvetra G
Prolan vet.	injection solution;	Bayer S

HCG, is not an anabolic/androgenic steroid but a natural protein hormone which develops in the placenta of a pregnant woman. HCG is manufactured from the urine of pregnant women since it is excreted in un-changed form from the blood via the woman's urine, passing through the kidneys. The commercially available HCG is sold as a dry substance and can be used both in men and women. in women injectable HCG allows for ovulation since it influences the last stages of the development of the ovum, thus stimulating ovulation. In a man HCG stimulates production of androgenic hormones (testosterone). For this reason athletes use injectable HCG to increase the testosterone produc-tion. HCG is often used in combination with anabolic/androgenic steroids during or after treatment. Since the body usually needs a certain amount of time to get its testosterone production going again, the athlete, after discontinuing steroid compounds, experiences a difficult transition phase which often goes hand in hand with a considerable loss in both strength and muscle mass. Administering HCG directly after steroid treatment helps to reduce this condition because HCG increases the testosterone production in the testes very quickly and reliably. In the event of testicular atrophy caused by mega doses and very long periods of usage, HCG also helps to quickly bring the testes back to their original condition (size). Since occasional injections of HCG during steroid intake can avoid a testicular atrophy, many athletes use HCG for two to three weeks in the middle of their steroid treatment. It is often observed that during this time the athlete makes his best progress with respect to gains in both strength and muscle mass. Those who are on the juice all year round, who might suffer psychological consequences or who would perhaps risk the breakup of a relationship because of this should consider this drawback when taking HCG in regular intervals. A reduced libido and spermatogenesis due to steroids, in most cases, can be successfully cured by treatment with HCG.

Most athletes, however, use HCG at the end of a treatment in order to avoid a "crash," that is, to achieve the best possible transition into "natural training." A precondition, however, is that the steroid intake or dosage be reduced slowly and evenly before taking HCG. Although HCG causes a quick and significant increase of the endogenic plasma- testosterone level, unfortunately it is not a perfect remedy to prevent the loss of strength and mass at the end of a steroid treatment. Although HCG does stimulate endogenous testosterone production, it does not help in reestablishing the normal hypothalamic/pituitary testicular axis. The hypothalamus and pituitary are still in a refractory state after prolonged steroid usage, and remain this way while HCG is being used, because the endogenous testosterone produced as a-result of the exogenous HCG represses the endogenous LH production. Once the HCG is discontinued, the athlete must still go through a re-adjustment period. This is merely delayed by the HCG use." For this reason experienced athletes often take Clomid and Clenbuterol following HCG intake or they immediately begin an-other steroid treatment. Some take HCG merely to get off the "steroids" for at least two to three weeks.

HCG package insert states clearly that HCG "has no known effect of fat mobilization, appetite or sense of hunger, or body fat distribution." It further states, "HCG has not been demonstrated to be effective adjunctive therapy in the treatment of obesity, it does not increase fat losses beyond that resulting from caloric restriction. 6000 I.U. of HCG in a single injection resulted in elevated testosterone levels for six days after the injection. At a dosage of 1500 I.U. the pharmatestosterone level increases by 250-300% (2.5-3fold) com-pared to the initial value. The athlete should inject one HCG ampule every 5 days. Since the testosterone level remains considerably elevated for several days, it is unnecessary to inject HCG more than once every 5 days. The effective dosage for athletes is usually 2000-5000 I.U. per injection and should-as al-ready mentioned-be injected every 5 days. HCG should only be taken for a few weeks. If HCG is taken by male athletes over many weeks and in high dosages, it is possible that the testes will respond poorly to a later HCG intake and a release of the body's own LH. This could result in a permanent inadequate gonadal function.

HCG can in part cause side effects similar to those of injectable testosterone. A higher testosterone production also goes hand in hand with an elevated estrogen level which could result in gynecomastia. This could manifest itself in a temporary growth of breasts or reinforce already existing breast growth in men. Farsighted athletes thus combine HCG with an antiestrogen. Male athletes also report more frequent erections and an increased sexual desire. In high doses it can cause acne vulgaris and the storing of minerals and water. The last point must especially be observed since the water retention which is possible through the use of HCG could give the muscle system a puffy and watery appearance. Athletes who have already increased their endogenous testosterone level by taking Clomid and intend subsequently to take HCG could experience considerable water retention and distinct feminization symptoms (gynecomastia, tendency toward fat de-posits on the hips). This is due to the fact that high testosterone leads to a high conversion rate to estrogens. In very young athletes HCG, like anabolic steroids, can cause an early stunting of growth since it prematurely closes the epiphysial growth plates. Mood swings and high blood pressure can also be attributed to the intake of HCG.

HCG's form of administration is also unusual. The substance choriongonadotropin is a white powdery freeze-dried substance which is usually used as a compress. Each package, for each HCG ampule, includes another ampule with an injection solution containing isotonic sodium chloride. This liquid, after both ampules have been opened in a sterile manner, is injected into the HCG ampule and mixed with the dried substance. The solution is then ready for use and should be injected intra-muscularly. If only part of the substance is injected the residual solution should be stored in the refrigerator. It is not necessary to store the unmixed HCG in the refrigerator; however, it should be kept out of light and below a temperature of 25* C.

HCG is a relatively expensive compound. It costs approx. $36 -45 for 3 ampules of 5000 I.U.

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